| Human | PDE1B | 1taz | A | B | | | |
| Human | PDE1B | 4npv | A | | 6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine | | |
| Human | PDE1B | 4npw | A | | 7,8-dimethoxy-N-[(2S)-1-(3-methyl-1H-pyrazol-5-yl)propan-2-yl]quinazolin-4-amine | | |
| Human | PDE1B | 5b25 | A | A | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | A | B | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | B | A | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | B | B | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | C | A | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | C | B | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | D | A | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5b25 | D | B | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one | | |
| Human | PDE1B | 5uoy | A | | 6-[(4-methoxyphenyl)methyl]-9-[(oxan-4-yl)methyl]-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one | | |
| Human | PDE1B | 5up0 | A | | 6-[(4-chlorophenyl)methyl]-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one | | |
| Human | PDE2A | 1z1l | A | A | | | |
| Human | PDE2A | 1z1l | A | B | | | |
| Human | PDE2A | 3ibj | A | | | | |
| Human | PDE2A | 3ibj | B | | | | |
| Human | PDE2A | 3itm | A | | | | |
| Human | PDE2A | 3itm | B | | | | |
| Human | PDE2A | 3itm | C | | | | |
| Human | PDE2A | 3itm | D | | | | |
| Human | PDE2A | 3itu | A | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE2A | 3itu | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE2A | 3itu | C | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE2A | 3itu | D | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE2A | 4c1i | A | | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | | |
| Human | PDE2A | 4c1i | B | | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | | |
| Human | PDE2A | 4c1i | C | | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | | |
| Human | PDE2A | 4c1i | D | | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | | |
| Human | PDE2A | 4d08 | A | A | 1-(5-butoxypyridin-3-yl)-4-methyl-8-(morpholin-4-ylmethyl)[1,2,4]triazolo[4,3-a]quinoxaline | | |