PDB-code
Browse PDE entries (page 30 of 31)
First 26 27 28 PreviousLast| # | Species | PDE Type | PDB | Chain | Alternate Model | Ligand | Details | File |
|---|---|---|---|---|---|---|---|---|
 | Human | PDE9A | 4y8c | A | 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one |  | ||
| Human | PDE9A | 4y8c | B | 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | | ||
| Leishmania | PDEB1 | 2r8q | A | 3-ISOBUTYL-1-METHYLXANTHINE | | ||
| Leishmania | PDEB1 | 2r8q | B | 3-ISOBUTYL-1-METHYLXANTHINE | | ||
| Trypanosoma brucei | PDEB1 | 4i15 | A | | |||
| Trypanosoma brucei | PDEB1 | 4i15 | B | | |||
| Trypanosoma brucei | PDEB1 | 4phl | A | A | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | | |
| Trypanosoma brucei | PDEB1 | 4phl | A | B | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | | |
| Trypanosoma brucei | PDEB1 | 4phl | B | A | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | | |
| Trypanosoma brucei | PDEB1 | 4phl | B | B | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | | |
| Trypanosoma brucei | PDEB1 | 5g2b | A | N-(2-amino-2-oxoethyl)-5'-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2'-methoxy[1,1'-biphenyl]-4-carboxamide | | ||
| Trypanosoma brucei | PDEB1 | 5g2b | B | N-(2-amino-2-oxoethyl)-5'-[(4aR,8aS)-3-cycloheptyl-4-oxo-3,4,4a,5,8,8a-hexahydrophthalazin-1-yl]-2'-methoxy[1,1'-biphenyl]-4-carboxamide | | ||
| Trypanosoma brucei | PDEB1 | 5g57 | A | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | ||
| Trypanosoma brucei | PDEB1 | 5g57 | B | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | ||
| Trypanosoma brucei | PDEB2 | 5h2q | A | A | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2q | A | B | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2q | B | A | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2q | B | B | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2r | A | A | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-(2-hydroxyethyloxy)-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2r | A | B | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-(2-hydroxyethyloxy)-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2r | B | A | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-(2-hydroxyethyloxy)-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma brucei | PDEB2 | 5h2r | B | B | (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-(2-hydroxyethyloxy)-3-[2-(2-oxidanylideneimidazolidin-1-yl)ethoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one | | |
| Trypanosoma cruzi | PDEC | 3v93 | A | | |||
| Trypanosoma cruzi | PDEC | 3v93 | B | | |||
| Trypanosoma cruzi | PDEC | 3v93 | C | | |||
| Trypanosoma cruzi | PDEC | 3v93 | D | | |||
| Trypanosoma cruzi | PDEC | 3v93 | E | | |||
| Trypanosoma cruzi | PDEC | 3v93 | F | | |||
| Trypanosoma cruzi | PDEC | 3v93 | G | | |||
| Trypanosoma cruzi | PDEC | 3v93 | H | |
This research was performed as part of the "Phosphodiesterase inhibitors for neglected parasitic diseases" (PDE4NPD) programme, which is supported by the European Union 7th Framework Program (FP7/2007-2013) under grant agreement n° 602666.
