| Human | PDE6-5-Chimera | 3jab | O | | | | |
| Human | PDE6-5-Chimera | 3jbq | B | | | | |
| Human | PDE6-5-Chimera | 3jbq | F | | | | |
| Human | PDE6-5-Chimera | 3jwq | A | | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE6-5-Chimera | 3jwq | B | | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE6-5-Chimera | 3jwq | C | | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE6-5-Chimera | 3jwq | D | | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE6-5-Chimera | 3jwr | A | | | | |
| Human | PDE6-5-Chimera | 3jwr | B | | | | |
| Human | PDE7A | 1zkl | A | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE7A | 3g3n | A | | 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one | | |
| Human | PDE7A | 4pm0 | A | | 2-(cyclopentylamino)-3-ethyl-7-ethynylthieno[3,2-d]pyrimidin-4(3H)-one | | |
| Human | PDE7A | 4y2b | A | | 3-ethyl-2-(propan-2-ylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one | | |
| Human | PDE8A | 3ecm | A | | | | |
| Human | PDE8A | 3ecn | A | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE8A | 3ecn | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 2hd1 | A | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 2hd1 | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 2yy2 | A | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 2yy2 | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 3dy8 | A | | GUANOSINE-5'-MONOPHOSPHATE | | |
| Human | PDE9A | 3dy8 | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 3dyl | A | | CYCLICGUANOSINEMONOPHOSPHATE | | |
| Human | PDE9A | 3dyl | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 3dyn | A | A | CYCLICGUANOSINEMONOPHOSPHATE | | |
| Human | PDE9A | 3dyn | A | B | CYCLICGUANOSINEMONOPHOSPHATE | | |
| Human | PDE9A | 3dyn | B | A | 3-ISOBUTYL-1-METHYLXANTHINE | | |
| Human | PDE9A | 3dyn | B | B | CYCLICGUANOSINEMONOPHOSPHATE | | |
| Human | PDE9A | 3dyq | A | | CYCLICGUANOSINEMONOPHOSPHATE | | |
| Human | PDE9A | 3dyq | B | | 3-ISOBUTYL-1-METHYLXANTHINE | | |