PDB-code
Browse PDE entries (page 26 of 31)
First 22 23 24 PreviousLast30 29 28 Next| # | Species | PDE Type | PDB | Chain | Alternate Model | Ligand | Details | File |
|---|---|---|---|---|---|---|---|---|
 | Human | PDE4D | 5k1i | F | 4-[(5-acetyl-2-ethyl-3-oxo-6-phenyl-2,3-dihydropyridazin-4-yl)amino]benzoic acid |  | ||
| Human | PDE4D | 5k1i | G | 4-[(5-acetyl-2-ethyl-3-oxo-6-phenyl-2,3-dihydropyridazin-4-yl)amino]benzoic acid | | ||
| Human | PDE4D | 5k1i | H | 4-[(5-acetyl-2-ethyl-3-oxo-6-phenyl-2,3-dihydropyridazin-4-yl)amino]benzoic acid | | ||
| Human | PDE4D | 5k32 | A | A | 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one | | |
| Human | PDE4D | 5k32 | A | B | 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one | | |
| Human | PDE4D | 5k32 | B | A | 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one | | |
| Human | PDE4D | 5k32 | B | B | 4-[(3-methoxyphenyl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one | | |
| Human | PDE4D | 5tkb | A | N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide | | ||
| Human | PDE4D | 5tkb | B | N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide | | ||
| Human | PDE4D | 5tkb | C | N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide | | ||
| Human | PDE4D | 5tkb | D | N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide | | ||
| Human | PDE4D | 5wqa | A | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde | | ||
| Human | PDE4D | 5wqa | B | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde | | ||
| Human | PDE5-4-Chimera | 1t9s | A | GUANOSINE-5'-MONOPHOSPHATE | | ||
| Human | PDE5-4-Chimera | 1t9s | B | GUANOSINE-5'-MONOPHOSPHATE | | ||
| Human | PDE5-4-Chimera | 1tbf | A | A | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE5-4-Chimera | 1tbf | A | B | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | |
| Human | PDE5-4-Chimera | 1xoz | A | 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE | | ||
| Human | PDE5-4-Chimera | 1xp0 | A | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE | | ||
| Human | PDE5-4-Chimera | 2chm | A | 5-[2-(BUT-3-EN-1-YLOXY)-5-(1-HYDROXYVINYL)PYRIDIN-3-YL]-3-ETHYL-2-(1-ETHYLAZETIDIN-3-YL)-1,2,6,7A-TETRAHYDRO-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE | | ||
| Human | PDE5-4-Chimera | 3hc8 | A | A | 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one | | |
| Human | PDE5-4-Chimera | 3hc8 | A | B | 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one | | |
| Human | PDE5-4-Chimera | 3hdz | A | A | 5-amino-1-butyl-7-phenyl-1,6-naphthyridin-4(1H)-one | | |
| Human | PDE5-4-Chimera | 3hdz | A | B | 5-amino-1-butyl-7-phenyl-1,6-naphthyridin-4(1H)-one | | |
| Human | PDE5-4-Chimera | 3tge | A | 7-(6-methoxypyridin-3-yl)-3-{[2-(morpholin-4-yl)ethyl]amino}-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one | | ||
| Human | PDE5-4-Chimera | 3tgg | A | 7-(6-methoxypyridin-3-yl)-4-{[2-(propan-2-yloxy)ethyl]amino}-1-(2-propoxyethyl)pyrido[4,3-d]pyrimidin-2(1H)-one | | ||
| Human | PDE5-4-Chimera | 5jo3 | B | 1-(5-chloro-6-methoxypyridin-3-yl)-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide | | ||
| Human | PDE5A | 1rkp | A | 3-ISOBUTYL-1-METHYLXANTHINE | | ||
| Human | PDE5A | 1t9r | A | A | | ||
| Human | PDE5A | 1t9r | A | B | |
This research was performed as part of the "Phosphodiesterase inhibitors for neglected parasitic diseases" (PDE4NPD) programme, which is supported by the European Union 7th Framework Program (FP7/2007-2013) under grant agreement n° 602666.
