PDB-code
Browse PDE entries (page 3 of 31)
First PreviousLast7 6 5 Next| # | Species | PDE Type | PDB | Chain | Alternate Model | Ligand | Details | File |
|---|---|---|---|---|---|---|---|---|
 | Human | PDE10 | 3ws8 | B | 8-methyl-6-[2-(5-methyl-1-phenyl-1H-benzimidazol-2-yl)ethyl]imidazo[1,5-a]pyrimidine |  | ||
| Human | PDE10 | 3ws9 | A | 7-[2-(5-methyl-1-phenyl-1H-benzimidazol-2-yl)ethyl]imidazo[1,5-b]pyridazine | | ||
| Human | PDE10 | 3ws9 | B | | |||
| Human | PDE10 | 3wyk | A | 3-(1-phenyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethyl)phenyl]pyridazin-4(1H)-one | | ||
| Human | PDE10 | 3wyk | B | 3-(1-phenyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethyl)phenyl]pyridazin-4(1H)-one | | ||
| Human | PDE10 | 3wyl | A | 5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethyl)phenyl]pyridazin-4(1H)-one | | ||
| Human | PDE10 | 3wyl | B | 5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethyl)phenyl]pyridazin-4(1H)-one | | ||
| Human | PDE10 | 3wym | A | 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one | | ||
| Human | PDE10 | 3wym | B | 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one | | ||
| Human | PDE10 | 4ael | A | 2-(2'-ETHOXYBIPHENYL-4-YL)-4-HYDROXY-1,6-NAPHTHYRIDINE-3-CARBONITRILE | | ||
| Human | PDE10 | 4ael | B | 2-(2'-ETHOXYBIPHENYL-4-YL)-4-HYDROXY-1,6-NAPHTHYRIDINE-3-CARBONITRILE | | ||
| Human | PDE10 | 4ajd | A | 2-ETHYL-4-METHYL-PHTHALAZIN-1-ONE | | ||
| Human | PDE10 | 4ajd | D | 2-ETHYL-4-METHYL-PHTHALAZIN-1-ONE | | ||
| Human | PDE10 | 4ajf | A | N-(4-OXO-3H-QUINAZOLIN-2-YL)ACETAMIDE | | ||
| Human | PDE10 | 4ajf | D | | |||
| Human | PDE10 | 4ajg | A | A | THIENO[3,2-C][1,6]NAPHTHYRIDINE | | |
| Human | PDE10 | 4ajg | A | B | THIENO[3,2-C][1,6]NAPHTHYRIDINE | | |
| Human | PDE10 | 4ajg | D | A | THIENO[3,2-C][1,6]NAPHTHYRIDINE | | |
| Human | PDE10 | 4ajg | D | B | THIENO[3,2-C][1,6]NAPHTHYRIDINE | | |
| Human | PDE10 | 4ajm | A | | |||
| Human | PDE10 | 4ajm | D | 3-AMINO-6-FLUORO-2-[4-(2-METHYLPYRIDIN-4-YL)PHENYL]-N-(METHYLSULFONYL)QUINOLINE-4-CARBOXAMIDE | | ||
| Human | PDE10 | 4bbx | A | 4-[3-[1-[(2S)-2-methoxypropyl]pyrazol-4-yl]-2-methyl-imidazo[1,2-a]pyrazin-8-yl]morpholine | | ||
| Human | PDE10 | 4bbx | B | 4-[3-[1-[(2S)-2-methoxypropyl]pyrazol-4-yl]-2-methyl-imidazo[1,2-a]pyrazin-8-yl]morpholine | | ||
| Human | PDE10 | 4ddl | A | 2-{1-[5-(6,7-dimethoxycinnolin-4-yl)-3-methylpyridin-2-yl]piperidin-4-yl}propan-2-ol | | ||
| Human | PDE10 | 4ddl | B | 2-{1-[5-(6,7-dimethoxycinnolin-4-yl)-3-methylpyridin-2-yl]piperidin-4-yl}propan-2-ol | | ||
| Human | PDE10 | 4dff | A | | |||
| Human | PDE10 | 4dff | B | 8,9-dimethoxy-1-(1,3-thiazol-5-yl)-5,6-dihydroimidazo[5,1-a]isoquinoline | | ||
| Human | PDE10 | 4fcb | A | A | 3,4-dimethyl-1-propyl-7-(quinolin-2-ylmethoxy)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 4fcb | A | B | 3,4-dimethyl-1-propyl-7-(quinolin-2-ylmethoxy)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 4fcb | B | A | 3,4-dimethyl-1-propyl-7-(quinolin-2-ylmethoxy)imidazo[1,5-a]quinoxaline | |
This research was performed as part of the "Phosphodiesterase inhibitors for neglected parasitic diseases" (PDE4NPD) programme, which is supported by the European Union 7th Framework Program (FP7/2007-2013) under grant agreement n° 602666.
