PDB-code
Browse PDE entries (page 2 of 31)
First Last6 5 4 Next| # | Species | PDE Type | PDB | Chain | Alternate Model | Ligand | Details | File |
|---|---|---|---|---|---|---|---|---|
 | Rat | PDE10 | 3hqz | A | A | 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline |  | |
| Rat | PDE10 | 3hqz | A | B | 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline | | |
| Rat | PDE10 | 3hr1 | A | A | 2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline | | |
| Rat | PDE10 | 3hr1 | A | B | 2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline | | |
| Rat | PDE10 | 3lxg | A | A | 2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Rat | PDE10 | 3lxg | A | B | 2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Rat | PDE10 | 3qpn | A | A | 6-methoxy-7-[2-(quinolin-2-yl)ethoxy]quinazoline | | |
| Rat | PDE10 | 3qpn | A | B | 6-methoxy-7-[2-(quinolin-2-yl)ethoxy]quinazoline | | |
| Rat | PDE10 | 3qpo | A | A | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline | | |
| Rat | PDE10 | 3qpo | A | B | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline | | |
| Rat | PDE10 | 3qpp | A | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline | | ||
| Human | PDE10 | 3sn7 | A | A | 8-fluoro-6-methoxy-3,4-dimethyl-1-(3-methylpyridin-4-yl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3sn7 | A | B | 8-fluoro-6-methoxy-3,4-dimethyl-1-(3-methylpyridin-4-yl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3sn7 | B | A | 8-fluoro-6-methoxy-3,4-dimethyl-1-(3-methylpyridin-4-yl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3sn7 | B | B | 8-fluoro-6-methoxy-3,4-dimethyl-1-(3-methylpyridin-4-yl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3sni | A | A | 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Human | PDE10 | 3sni | A | B | 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Human | PDE10 | 3sni | B | A | 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Human | PDE10 | 3sni | B | B | 2-methoxy-6,7-dimethyl-9-(4-methylpyridin-3-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazine | | |
| Human | PDE10 | 3snl | A | A | | ||
| Human | PDE10 | 3snl | A | B | | ||
| Human | PDE10 | 3snl | B | A | 6-chloro-3,4-dimethyl-1-(3-methylpyridin-4-yl)-8-(trifluoromethyl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3snl | B | B | 6-chloro-3,4-dimethyl-1-(3-methylpyridin-4-yl)-8-(trifluoromethyl)imidazo[1,5-a]quinoxaline | | |
| Human | PDE10 | 3ui7 | A | 6-methoxy-3,8-dimethyl-4-(morpholin-4-ylmethyl)-1H-pyrazolo[3,4-b]quinoline | | ||
| Human | PDE10 | 3ui7 | B | 6-methoxy-3,8-dimethyl-4-(morpholin-4-ylmethyl)-1H-pyrazolo[3,4-b]quinoline | | ||
| Human | PDE10 | 3uuo | A | 6-methoxy-3,8-dimethyl-4-(piperazin-1-yl)-1H-pyrazolo[3,4-b]quinoline | | ||
| Human | PDE10 | 3uuo | B | 6-methoxy-3,8-dimethyl-4-(piperazin-1-yl)-1H-pyrazolo[3,4-b]quinoline | | ||
| Human | PDE10 | 3wi2 | A | 2-({[1-phenyl-2-(propan-2-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline | | ||
| Human | PDE10 | 3wi2 | B | 2-({[1-phenyl-2-(propan-2-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline | | ||
| Human | PDE10 | 3ws8 | A | 8-methyl-6-[2-(5-methyl-1-phenyl-1H-benzimidazol-2-yl)ethyl]imidazo[1,5-a]pyrimidine | |
This research was performed as part of the "Phosphodiesterase inhibitors for neglected parasitic diseases" (PDE4NPD) programme, which is supported by the European Union 7th Framework Program (FP7/2007-2013) under grant agreement n° 602666.
